Understanding eGFR
and How Renadyl® Helps
What is eGFR?
eGFR (estimated Glomerular Filtration Rate) measures how efficiently your kidneys filter waste from your blood. Rather than a single lab value, eGFR estimates overall kidney function using markers such as creatinine, cystatin C, age, sex, and sometimes race.
- Higher eGFR → better kidney filtration
- Lower eGFR → reduced kidney function and potential accumulation of waste in the blood
eGFR variations can be influenced by factors such as muscle mass, medications, and other health conditions.
Monitoring eGFR is critical for early detection of kidney stress, chronic kidney disease, or declining renal function. Talk to your doctor if you have or suspect changes.
Creatinine-Based vs. Cystatin C-Based eGFR
Understanding both creatinine- and cystatin C–based eGFR helps you get a clearer picture of your kidney health. Because creatinine can be influenced by muscle mass and diet, cystatin C offers an additional and often more accurate measure, giving you greater confidence in your kidney function results. Some labs combine creatinine and cystatin C to calculate a more precise eGFR.
- Creatinine-Based eGFR
- Uses blood creatinine levels as the primary marker.
- Creatinine is a waste product from muscle metabolism, filtered by the kidneys.
- Influenced by muscle mass, diet, and hydration, so values can vary among individuals.
- Cystatin C-Based eGFR
- Uses cystatin C, a protein produced by all nucleated cells, as a filtration marker.
- Less affected by muscle mass or diet, providing a more accurate estimate in certain cases.
What Does Your eGFR Number Mean?
In healthy adults, a normal eGFR typically ranges from 90–120 mL/min/1.73 m², reflecting efficient kidney filtration. Even modest reductions in eGFR can indicate that kidneys are under stress. eGFR naturally declines slightly with age, so what’s “normal” can vary depending on age, body composition, and overall health. Talk to your doctor about your eGFR test results or if you suspect changes.
| eGFR Range (mL/min/1.73 m²) | Kidney Function Status | Interpretation |
|---|---|---|
| 90-120 | Normal / Optimal | Kidneys are filtering efficiently |
| 60-89 | Mildly decreased | Early kidney stress or age-related decline; usually symptom-free |
| 45-59 | Mild to moderate decrease | Early-stage kidney disease may be present |
| 30-44 | Moderate to severe decrease | Kidney function significantly reduced; medical management recommended |
| 15-29 | Severe decrease | Advanced kidney disease; close medical supervision needed |
| <15 | Kidney failure | Critically low filtration; dialysis or transplant may be required |
The Gut–Kidney Connection - How Your Gut Influences eGFR
eGFR measures how well your kidneys filter waste, and gut health can play a surprising role in supporting this number.
- Your gut helps process waste products and toxins before they reach the bloodstream, which directly affects how hard your kidneys need to work.
- When the gut is functioning well, fewer harmful substances circulate, and the kidneys can filter more efficiently, helping support a healthier eGFR.
- When the gut becomes imbalanced, more toxins and irritants can enter the bloodstream, increasing kidney strain and potentially contributing to a lower eGFR.
The good news? Supporting gut health with Renadyl helps ease the kidneys’ workload by reducing waste and toxins before they enter the bloodstream, helping maintain steadier, healthier eGFR levels over time.
How Renadyl Supports Kidney Function and eGFR
Renadyl is a clinically studied probiotic designed to help support healthy kidney function, an essential factor in maintaining a stable estimated glomerular filtration rate (eGFR). Its proprietary strains — Streptococcus thermophilus, Lactobacillus acidophilus, and Bifidobacterium longum — were selected for their ability to metabolize nitrogenous waste and other uremic toxins within the gut.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Here’s How Renadyl Helps:
- Helps Reduce Waste Before It Enters the Bloodstream Renadyl’s probiotic strains work in the gut to metabolize waste products that would otherwise make their way into the bloodstream. By lowering this burden, the kidneys can filter more efficiently, helping support healthier eGFR levels.
- Limits Toxins That Can Lower eGFR Renadyl helps break down harmful compounds like indoxyl sulfate and p-cresol sulfate that contribute to kidney stress. With fewer of these toxins circulating, the kidneys can perform their filtration role more effectively.
- Supports Overall Kidney Efficiency By promoting better waste processing and reducing inflammatory irritants, Renadyl helps maintain an internal environment that supports optimal kidney function — which is reflected in more stable eGFR readings.
Concerned About Your eGFR Levels?
Talk to your doctor about taking one Renadyl capsule twice a day consistently for at least six months. Combine with good hydration and a kidney-friendly diet for best results.
Backed by Research
Studies indicate that Renadyl can:
- Reduce gut-derived uremic toxins
- Support BUN, creatinine, uric acid, and eGFR markers
- Improve overall energy and well-being in individuals managing kidney stress
Learn more about kidney health research:
National Institutes of Health – NIH.gov
National Kidney Foundation – eGFR Explained
Tips to Maintain Healthy eGFR Naturally
- Control blood sugar and blood pressure.
- Follow a kidney-friendly diet.
- Stay hydrated.
- Exercise regularly.
- Avoid kidney stressors like NSAIDs, excessive alcohol, and smoking.
Stay Informed About Kidney Health and Gut Science.
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FAQs About Creatinine and Renadyl
Can probiotics really help with eGFR in CKD?
Yes. Renadyl helps reduce gut-derived toxins that can stress the kidneys, supporting healthier kidney function and helping maintain eGFR.
Is Renadyl safe for CKD patients?
Yes, it’s generally safe. Always check with your healthcare provider before starting any supplement.
Can Renadyl replace medications for CKD?
No. Renadyl® is a supplement that works alongside your doctor’s treatments, diet, and lifestyle changes.
Are there any side effects?
Most users tolerate probiotics well. Mild digestive changes may occur at first; contact your doctor if you have concerns.
Learn More About Other Key Kidney Function Markers
Maintain Healthy Kidney Function with Renadyl
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